The effect-site concentration of remifentanil for blunting hemodynamic responses: comparative study in single-lumen endotracheal and double-lumen endobronchial intubation
Anesthesia and Pain Medicine
;
: 247-250, 2017.
Artigo
em Coreano
| WPRIM
| ID: wpr-145723
ABSTRACT
BACKGROUND:
This study undertook to compare the effect-site concentration of remifentanil for prevention of hemodynamic responses to endotracheal intubation, employing the single-lumen tracheal tube and the double-lumen bronchial tube during total intravenous anesthesia.METHODS:
Based on the nature of the surgery, 38 patients undergoing general anesthesia were assigned either to the single-lumen tube group or the double-lumen tube group. Anesthesia was induced by a target controlled infusion of propofol, with an effect-site concentration of 4 µg/ml. Remifentanil was then administered to the first patient in each group, with an effect-site concentration of 3.5 ng/ml. Subsequent concentration of remifentanil was determined by hemodynamic responses of the previous patient to intubation, based on the up-and-down method.RESULTS:
The effect-site concentrations of remifentanil for prevention of hemodynamic responses to endotracheal intubation in 50% of patients (EC₅₀) were 2.8 ng/ml (95% CI, 2.0–3.7 ng/ml) in the single-lumen tube group, and 2.9 ng/ml (95% CI, 2.5–3.2 ng/ml) in the double-lumen tube group. No significant difference was observed between the two groups.CONCLUSIONS:
The effect-site concentration of remifentanil for prevention of hemodynamic responses to endotracheal intubation did not differ during total intravenous anesthesia, using either the single-lumen tracheal tube or the double-lumen bronchial tube.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Propofol
/
Hemodinâmica
/
Intubação
/
Intubação Intratraqueal
/
Anestesia
/
Anestesia Geral
/
Anestesia Endotraqueal
/
Anestesia Intravenosa
/
Métodos
Limite:
Humanos
Idioma:
Coreano
Revista:
Anesthesia and Pain Medicine
Ano de publicação:
2017
Tipo de documento:
Artigo
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