Effect of Sodium Bicarbonate or Lidocaine Mixed with Rocuronium on Withdrawal Movement during Rocuronium Injection / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 160-163, 2004.
Artigo
em Coreano
| WPRIM
| ID: wpr-146191
ABSTRACT
BACKGROUND:
We have often observed arm withdrawal on administering rocuronium. This study was performed to determine the cause and to prevent this movement by mixing rocuronium with lidocaine or sodium bicarbonate.METHODS:
Sixty-two patients, ASA I-II, were randomized into three groups for this blind, prospective study. After induction of anesthesia by thiopental sodium 0.5 mg/kg, each group received rocuronium 0.6 mg/kg alone (group R), with 2% (2 ml) lidocaine (group L), or rocuronium with an equivalent volume of 8.4% sodium bicarbonate (group S). Patients' responses to the injection were graded using a 4-point scale and the pHs of the mixtures were measured.RESULTS:
The incidence rate of arm withdrawal was more reduced in groups L (47%) and S (45%) than in group R (80%) (P < 0.05). Severe withdrawal movement (grade 3) did not occur in group S (0%).CONCLUSIONS:
The incidence and the degree of withdrawal movement in response to the injection of rocuronium were significantly reduced by mixing an equivalent volume of 8.4% sodium bicarbonate with rocuronium.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Braço
/
Sódio
/
Tiopental
/
Incidência
/
Estudos Prospectivos
/
Bicarbonato de Sódio
/
Concentração de Íons de Hidrogênio
/
Anestesia
/
Lidocaína
Tipo de estudo:
Ensaio Clínico Controlado
/
Estudo de incidência
/
Estudo observacional
/
Estudo prognóstico
Limite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Anesthesiology
Ano de publicação:
2004
Tipo de documento:
Artigo
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