Availability of Troponin I and T and CK-MB for Diagnosis of Acute Myocardial Infarction in Patients of Renal Failure Admited to an Emergency Medical Center
Journal of the Korean Society of Emergency Medicine
;
: 485-488, 2002.
Artigo
em Coreano
| WPRIM
| ID: wpr-147258
ABSTRACT
PURPOSE:
Generally, if a patient suffers from chest pain and shows a specific EKG pattern, it is easy to determine a clinical diagnosis, thus it is but in many cases, patients show nonspecific chest pain and a nonspecific EKG pattern. So it's important to consider the serological labaratory exam for cardiac enzymes for a definite diagnosis. Until now, cTnI has been considered to be different from CK-MB and cTnT in that it shows a specific elevation in early myocardiac injury and rare nonspecific elevation in renal-failure patients. Therefore, to affirm a sufficient relation between cTnI elevation and myocardiac injury, are carried out this study.METHODS:
The number of patients in the study was 58. No one had shown any evidence of myocardiac injury during the recent 2 years or any of the risk factors for AMI, such as smoking, obesity, and hypercholesterolemia. They showed specific symptoms like chest pain or nonspecific ones like dyspnea, indigestion, or a nonspecific EKG abnormality, including nonspecific ST-T change. Their serum creatinine level was above 2.0 mg/dL and qualitative results of cTnI was obtained by using a Troponin I rapid assay kit. The definite diagnosis of AMI was made by a cardiologist based on an intergrated result of EKG, clinical symptoms and signs and regional cardiac wall-motion abnormality on a echocardiogram.RESULTS:
The sensitivity of CK-MB, cTnT, and cTnI were 100%, 100%, and 100%, respectively, and the specificities were 75%, 85%, 100%.CONCLUSION:
In cases of patients with a high serum-creatinine level, particularly, those with positive serum CK-MB and cTnT, the measurement of cTnI is considered to be significant for the differential diagnosis of AMI as it shows both a high sensitivity and a high specificity in early myocardiac injury.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fumaça
/
Troponina
/
Dor no Peito
/
Fumar
/
Fatores de Risco
/
Sensibilidade e Especificidade
/
Troponina I
/
Creatinina
/
Diagnóstico
/
Diagnóstico Diferencial
Tipo de estudo:
Estudo diagnóstico
/
Estudo de etiologia
/
Pesquisa qualitativa
/
Fatores de risco
Limite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Society of Emergency Medicine
Ano de publicação:
2002
Tipo de documento:
Artigo
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