Effects of Dimethyl Sulfoxide on the Differentiation of Myocardial and Endothelial Cells / 영남의대학술지
Yeungnam University Journal of Medicine
; : 111-119, 1988.
Article
em Ko
| WPRIM
| ID: wpr-147314
Biblioteca responsável:
WPRO
ABSTRACT
To elucidate the effects of dimethyl sulfoxide on of myocardial and endothelial cells in culture, the cells were exposed to 10% dimethyl sulfoxide in culture medium for 1 hour at 48 hours after cell isolation. The general morphology and the cytochemical reaction of marker enzymes for mitochondria and Golgi complexes were investigated. The results were summarized as follows 1. DMSO induced elongation and narrowing of the cells and increase of mitochondrial reaction in myocardial cells. 2. DMSO induced destruction and disruption of myofibrils in myocardial cells resulting in increase of contractile activities. 3. In the endothelial cells, DMSO suppressed proliferative activities but thiamine pyrophosphatase reactions were enhanced indicating increase of Golgi complex activity. 4. DMSO seemed to hamper with the adhesiveness and motility of the endothelial cells causing the decrease of the number of cells in vitro.
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Tiamina Pirofosfatase
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Técnicas In Vitro
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Separação Celular
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Adesividade
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Dimetil Sulfóxido
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Células Endoteliais
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Complexo de Golgi
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Mitocôndrias
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Miofibrilas
Idioma:
Ko
Revista:
Yeungnam University Journal of Medicine
Ano de publicação:
1988
Tipo de documento:
Article