Bone and Metabolic Markers in Women With Recurrent Calcium Stones
Korean Journal of Urology
;
: 177-182, 2013.
Artigo
em Inglês
| WPRIM
| ID: wpr-147379
ABSTRACT
PURPOSE:
The target of our work was to study several biochemical parameters in phospho-calcic and bone metabolism in blood and urine and the bone mineral density of women with recurrent calcium nephrolithiasis. MATERIALS ANDMETHODS:
We conducted a cross-sectional study with a control group of 85 women divided into 3 groups group 1 consisted of 25 women without a history of nephrolithiasis, group 2 consisted of 35 women with only one episode of calcium nephrolithiasis, and group 3 consisted of 25 women with a history of recurrent calcium nephrolithiasis. Blood and urine biochemical study was performed, including markers related to lithiasis, and a bone mineral density study was done by use of bone densitometry.RESULTS:
Patients in group 3 showed statistically significantly elevated calciuria (15.4 mg/dL), fasting calcium/creatinine ratio (0.14), and 24-hour calcium/creatinine ratio (0.21) compared with groups 1 and 2. Moreover, this group of women with recurrent calcium nephrolithiasis had significantly elevated values of beta-crosslaps, a bone resorption marker, compared with groups 1 and 2 (p=0.000) and showed more bone mineral density loss than did these groups.CONCLUSIONS:
Recurrent calcium nephrolithiasis in women has a significant association with bone mineral density loss and with values of calciuria, both fasting and 24-hour.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Reabsorção Óssea
/
Densidade Óssea
/
Cálcio
/
Estudos Transversais
/
Jejum
/
Litíase
/
Nefrolitíase
/
Urolitíase
Tipo de estudo:
Estudo observacional
/
Estudo de prevalência
/
Fatores de risco
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Korean Journal of Urology
Ano de publicação:
2013
Tipo de documento:
Artigo
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