The Effect of Splenectomy on Acute Barium Sulfate Induced Toxicity of Rat Organs
Korean Journal of Pathology
;
: 249-257, 2004.
Artigo
em Coreano
| WPRIM
| ID: wpr-148779
ABSTRACT
BACKGROUND:
The purpose of this study was to elucidate whether or not splenectomy alters the acute toxic effects on rat tissue induced by barium sulfate.METHODS:
A total of 80 Sprague-Dawely male rats were divided into three groups; the control group and the barium sulfate treated groups with and without splenectomy. The pathologic changes in the solid organs were examined at the time after intraperitoneal treatment with barium sulfate. The changes of white blood cell count were also examined.RESULTS:
The barium induced toxicity was most prominent in the spleen. The changes in the other organs were proportional to the experimental duration, and the changes in the barium only treatment group were more severe than the observed changes in the splenectomy and barium treated group.CONCLUSIONS:
These results suggest that the degree of barium toxicity of barium only treated group was more severe than that of the splenectomy group.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Baço
/
Esplenectomia
/
Bário
/
Sulfato de Bário
/
Contagem de Leucócitos
Limite:
Animais
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Korean Journal of Pathology
Ano de publicação:
2004
Tipo de documento:
Artigo
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