A Case of Ethylene Glycol intoxication with Acute Renal Injury: Successful Recovery by Fomepizole and Renal Replacement Therapy
Electrolytes & Blood Pressure
;
: 47-51, 2017.
Artigo
em Inglês
| WPRIM
| ID: wpr-149586
ABSTRACT
Ethylene glycol is a widely used and readily available substance. Ethylene glycol ingestion does not cause direct toxicity; however, its metabolites are highly toxic and can be fatal even in trace amounts. Poisoning is best diagnosed through inquiry, but as an impaired state of consciousness is observed in most cases, poisoning must be suspected when a significantly elevated osmolar gap or high anion gap metabolic acidosis is found in blood tests. Hemodialysis and alcohol dehydrogenase inhibitors such as ethanol and fomepizole are a part of the basic treatment, and timely diagnosis and treatment are crucial because any delays can lead to death. However, there are few reported cases in Korea, and no report on the use of fomepizole. Herein, we report a case of acute renal failure caused by ethylene glycol poisoning that was treated with fomepizole and hemodialysis and present a literature review.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Intoxicação
/
Equilíbrio Ácido-Base
/
Acidose
/
Álcool Desidrogenase
/
Diálise Renal
/
Terapia de Substituição Renal
/
Estado de Consciência
/
Etilenoglicol
/
Diagnóstico
/
Etanol
Tipo de estudo:
Estudo diagnóstico
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Electrolytes & Blood Pressure
Ano de publicação:
2017
Tipo de documento:
Artigo
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