Plaque stage of Dermatofibrosarcoma Protuberans / 대한피부과학회지

ABSTRACT

We report a case of plaque stage of dermatofibrosarcoma protuberans(DFSP). A 36-year-old female visited our clinic with a 10-year history of solitary deep seated palpable erythematous plaque on right anterior chest. There was no history of previous trauma at the site of the lesion. Histopathologic findings are characterized by a flat surface, lower cellularity and slender spindle-shaped neoplastic cells diffusely infiltrated dermis and subcutaneous tissue. The slender neoplastic cells have uniform nuclei with no evidence of cytologic atypia. Especially earlier plaque or nonprotuberans stage of the DFSP could be confused with benign lesions such as dermatofibroma or diffuse neurofibroma. Because plaque areas are strongly positive for CD34, this antibody is very helpful in differentiating other benign tumors.