Your browser doesn't support javascript.
loading
Initial Electrocardiographic Findings Associated with Failed Resolution of ST-segment Elevation after Thrombolytic Therapy in Acute ST-segment Elevation Myocardial Infarction (STEMI)
Journal of the Korean Society of Emergency Medicine ; : 345-352, 2012.
Artigo em Inglês | WPRIM | ID: wpr-150128
ABSTRACT

PURPOSE:

Electrocardiography is a non-invasive tool for use in prediction of reperfusion and outcome of acute myocardial infarction. We attempted to determine initial electrocardiographic findings associated with failed resolution of ST-segment elevation (STE) among patients with ST-segment Elevation Myocardial Infarction (STEMI) treated with a thrombolytic agent.

METHODS:

This retrospective study included patients with STEMI who were treated with a thrombolytic agent at the emergency department between October 2008 and March 2011. During the study period, among 331 patients with STEMI, 43 patients were enrolled. Resolution of STE was evaluated by comparison of initial electrocardiography (ECG) with follow-up ECG, taken 90 minutes after thrombolytic therapy. Determination of success or failure of resolution of STE was based on the electrocardiographic criteria of the American College of Cardiology and the American Heart Association (ACC/AHA). Patients were divided into two groups according to these criteria, and initial electrocardiographic findings were compared for the two groups.

RESULTS:

Of a total of 43 patients, 22(55.16%) demonstrated failed resolution of STE after thrombolytic therapy. The risk of failed resolution of STE was approximately nine times higher in the anterior location of STE, compared to the inferior location of STE (OR 9.09, 95% CI, 1.46-94.69, p<0.01). In addition, the absence of reciprocal ST depression was associated with a six times higher risk of failed resolution of STE, compared with the presence of reciprocal ST depression (OR 6, 95% CI, 1.17-39.23, p=0.01). However, other electrocardiographic findings, including abnormal Q-wave, wide QRS complex, and QTc prolongation did not differ statistically between the two groups.

CONCLUSION:

Failed STE resolution after thrombolytic therapy was more frequent in STEMI patients with ST elevation in an anterior location or without reciprocal ST depression.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Cardiologia / Reperfusão / Terapia Trombolítica / Estudos Retrospectivos / Seguimentos / Depressão / Eletrocardiografia / Emergências / American Heart Association / Infarto do Miocárdio Tipo de estudo: Estudo diagnóstico / Estudo observacional / Estudo prognóstico / Fatores de risco Limite: Humanos Idioma: Inglês Revista: Journal of the Korean Society of Emergency Medicine Ano de publicação: 2012 Tipo de documento: Artigo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Cardiologia / Reperfusão / Terapia Trombolítica / Estudos Retrospectivos / Seguimentos / Depressão / Eletrocardiografia / Emergências / American Heart Association / Infarto do Miocárdio Tipo de estudo: Estudo diagnóstico / Estudo observacional / Estudo prognóstico / Fatores de risco Limite: Humanos Idioma: Inglês Revista: Journal of the Korean Society of Emergency Medicine Ano de publicação: 2012 Tipo de documento: Artigo