A Case of Early Gastric Adenocarcinoma and Intraabdominal Schwannoma in a Patient with Neurofibromatosis Type I / 대한소화기내시경학회지
Korean Journal of Gastrointestinal Endoscopy
;
: 83-87, 2007.
Artigo
em Coreano
| WPRIM
| ID: wpr-15092
ABSTRACT
Neurofibromatosis is an autosomal dominant hereditary disorder with an overall incidence of one in 3,000~4,000, and type 1 (Von Recklinghausen's neurofibromatosis) characterized by the presence of multiple cutaneous neurofibromas, axillary and groin freckling, and cafe- au-lait spot. The neurofibromatosis type 1 gene is a tumor suppressor gene. Patients with the neurofibromatosis type 1 are at increased risk of developing nervous system neoplasm, including plexiform neurofibromas, optic gliomas, ependymomas, meningiomas, astrocytomas, and pheochromocytomas. Neurofibromas may undergo secondary malignant degeneration and sarcomatous changes. Patients with neurofibromatosis type 1 show a high incidence of Wilm's tumor, rhabdomyosarcoma, nonlymphocytic leukemia, and pheochromocytoma but the gastrointestinal involvement appears to be relatively rare and usually consists of neurofibroma, ganglioneuroma, and leiomyoma. We have identified a case of early gastric adenocarcinoma and intraabdominal schwannoma in a 65-year-old man afflicted with neurofibromatosis type 1.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Feocromocitoma
/
Rabdomiossarcoma
/
Astrocitoma
/
Adenocarcinoma
/
Leucemia
/
Incidência
/
Genes Supressores de Tumor
/
Neurofibromatose 1
/
Neurofibromatoses
/
Neurofibroma Plexiforme
Tipo de estudo:
Estudo de incidência
/
Estudo prognóstico
Limite:
Idoso
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Gastrointestinal Endoscopy
Ano de publicação:
2007
Tipo de documento:
Artigo
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