Your browser doesn't support javascript.
loading
Immunohistochemical localization of galectin-3 in the granulomatous lesions of paratuberculosis-infected bovine intestine
Journal of Veterinary Science ; : 177-180, 2009.
Artigo em Inglês | WPRIM | ID: wpr-151429
ABSTRACT
The presence of galectin-3 was immunohistochemically quantified in bovine intestines infected with paratuberculosis (Johne's disease) to determine whether galectin-3 was involved in the formation of granulation tissue associated with the disease. Mycobacterium avium subsp. paratuberculosis infection was histochemically confirmed using Ziehl-Neelsen staining and molecularly diagnosed through rpoB DNA sequencing. Galectin-3 was detected in the majority of inflammatory cells, possibly macrophages, in the granulomatous lesions within affected tissues, including the ileum. These findings suggest that galectin-3 is associated with the formation of chronic granulation tissues in bovine paratuberculosis, probably through cell adhesion and anti-apoptosis mechanisms.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Paratuberculose / RNA Polimerase II / Imuno-Histoquímica / Doenças dos Bovinos / Doença Crônica / Galectina 3 / Intestino Delgado Limite: Animais Idioma: Inglês Revista: Journal of Veterinary Science Ano de publicação: 2009 Tipo de documento: Artigo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Paratuberculose / RNA Polimerase II / Imuno-Histoquímica / Doenças dos Bovinos / Doença Crônica / Galectina 3 / Intestino Delgado Limite: Animais Idioma: Inglês Revista: Journal of Veterinary Science Ano de publicação: 2009 Tipo de documento: Artigo