Catheter-directed Thrombolysis of Below-Knee Deep Venous Thrombosis of the Lower Extremities
Journal of the Korean Radiological Society
;
: 121-125, 2008.
Artigo
em Coreano
| WPRIM
| ID: wpr-151894
ABSTRACT
PURPOSE:
To evaluate the technical feasibility and clinical efficacy of the use of local thrombolysis for below-knee deep vein thrombosis (DVT). MATERIALS ANDMETHODS:
From a population of 41 patients with a lower extremity DVT, the prospective clinical trial included 11 patients (7 female, 4 male, average age 61.4 years) treated with catheter-directed thrombolysis with urokinase for below-knee DVT. After removal of the proximal ilofemoral DVT, additional interventional procedures to remove the residual thrombus and restore the venous flow from the below-knee vein were performed in cases of continuous occlusion of venous flow from the popliteal and tibial veins. Under ultrasound (US) guidance, catheter-directed thrombolysis with urokinase was performed through the ipsilateral popliteal vein. After administration of oral anticoagulation therapy, CT and venography were performed to identify patency and the presence of a recurrent thrombosis.RESULTS:
Successful removal of the thrombus and restoration of venous flow were achieved in all of the patients (100%). Restoration of flow with a residual thrombus occurred in one case. Focal venous stenosis was discovered in four cases. The duration of urokinase infusion was 1-4 days (average 2.36 days), which was considered long. For 15.2 months, the venous lumen of all cases was preserved without a recurrent thrombosis.CONCLUSION:
Catheter-directed thrombolysis is an effective procedure for recanalization of below-knee DVT in patients with a lower extremity DVT.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Veia Poplítea
/
Trombose
/
Veias
/
Flebografia
/
Ativador de Plasminogênio Tipo Uroquinase
/
Terapia Trombolítica
/
Estudos Prospectivos
/
Constrição Patológica
/
Trombose Venosa
/
Extremidade Inferior
Tipo de estudo:
Guia de Prática Clínica
/
Estudo observacional
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Journal of the Korean Radiological Society
Ano de publicação:
2008
Tipo de documento:
Artigo
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