Management of Conjunctival Squamous Cell Carcinoma with Cryotherapy, and Amniotic Membrane Graft

ABSTRACT

PURPOSE: We reported the surgical efficacy of amniotic membrane graft with cryotherapy, after primary surgical resection of the conjunctival squamous cell carcinoma METHODS: Three cases of conjunctival squamous cell carcinoma were completely resected with two layered cryotherapy along inner and outer side of tumor margin The extensive conjunctival defect was reconstructed with amniotic membrane graft. We evaluated the surgical effect and recurrence of conjunctival squamous cell carcinoma after surgery. RESULTS: Conjunctiva and cornea were completely healed with no recurrence, during the follow up of 8 months, 18 months, and 22 months, respectively. CONCLUSIONS: Surgical excision with adjunctive cryotherapy in peripheral area of the tumor margin and amniotic membrane transplantation could be considered effective method for treatment of conjunctival squamous cell carcinoma.