A Case of Tenofovir-associated Fanconi Syndrome in Patient with Chronic Hepatitis B / 대한소화기학회지
The Korean Journal of Gastroenterology
;
: 317-320, 2016.
Artigo
em Coreano
| WPRIM
| ID: wpr-153201
ABSTRACT
Tenofovir disoproxil fumarate (TDF) is one of the most widely used treatment options for human immunodeficiency virus (HIV) and HBV infections. Despite its efficacy and safety, some cases of nephrotoxicity have been reported in the treatment of HIV patients. Even more recently, very few cases of Fanconi syndrome associated with tenofovir therapy in HBV monoinfection have been reported. Herein, we report a case of a 47-year-old male with an HBV monoinfection, who developed Fanconi syndrome and a secondary osteomalacia with multiple bone pain. After TDF withdrawal and supplementation of calcitriol, his renal function was reverted. Although the overall risk of TDF-associated nephrotoxicity is very low, both glomerular and tubular function should be monitored in patients undergoing TDF treatment.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Osteomalacia
/
Calcitriol
/
Vírus da Hepatite B
/
HIV
/
Hepatite B Crônica
/
Síndrome de Fanconi
/
Tenofovir
/
Hepatite Crônica
/
Túbulos Renais
Limite:
Humanos
/
Masculino
Idioma:
Coreano
Revista:
The Korean Journal of Gastroenterology
Ano de publicação:
2016
Tipo de documento:
Artigo
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