Interstitial Pneumonitis in a Patient with Chronic Hepatitis C and Chronic Renal Failure on Interferon Therapy / 대한소화기학회지
The Korean Journal of Gastroenterology
;
: 47-52, 2011.
Artigo
em Inglês
| WPRIM
| ID: wpr-153658
ABSTRACT
After 4-months of alpha interferon (IFN-alpha), a 64-year old woman with chronic hepatitis C developed a cough and dyspnea and showed diffuse infiltrative opacities on her chest X-ray. Her symptoms persisted after stopping the IFN-alpha therapy. Pulmonary function testing revealed a reduced forced vital capacity. High-resolution computed tomography of the lung showed peripheral and peribronchovascular ground glass attenuation and consolidation associated with reticulation. Bronchoalveolar lavage was performed for further evaluation and showed a lymphocyte level of 8.2%, an uncommon finding in IFN-alpha-induced interstitial pneumonitis. We performed a lung biopsy to diagnose her disease and it suggested interstitial pneumonitis. This was considered to be due to the immunomodulatory effects of INF-alpha. Although rare, any sign of significant pulmonary involvement should be evaluated.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Antivirais
/
Testes de Função Respiratória
/
Tomografia Computadorizada por Raios X
/
Interferon-alfa
/
Doenças Pulmonares Intersticiais
/
Lavagem Broncoalveolar
/
Hepatite C Crônica
/
Falência Renal Crônica
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
The Korean Journal of Gastroenterology
Ano de publicação:
2011
Tipo de documento:
Artigo
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