The Incidence of HBs Antigenemia in Glomerular Desease and Control Group in Children

ABSTRACT

HBsAg, HBcAb and HBsAb were examined with radio-immunoassay in 265 patients with glomerular disease, who were admitted to wards or visited to outpatient clinics of department of pediatrics, Seoul National University Hospital, from Jan., 78 to Oct. 80, and in 576 control group, with other than liver disease and without history of transfusion. The incidence in glomerular disease was 10.2%(27 of 265 patients)-nephrotic syndrome 9.2%(12 of 130); acute glomerulonephritis 7.3%(5 of 68), recurrent hematuria 7.7%(2 of 26), H-S nephritis 25%(3 of 12), chronic renal failure 21%(3 of 14), and the others 13.3%(2 of 15), while the incidence of HBs antigenemia in control group was 5.03%(29 of 576 patients)-male 5.5%(21 of 362), female 4.2%(8 of 214). The overall incidence of HBs antigenemia in renal disease was statistically higher than that of control group(p<0.05), though the respective incidences of the above each renal disease group were somewhat higher than that of control group, however they were not statistically significant, The incidence of positive rate of HBsAb and/or HBcAb in control group was 26.7%(56 of 209), and that in renal disease was 23%(18 of 578).