Long-term Clinical and Angiographic Results of Coronary Stenting in Diabetic Patients

ABSTRACT

BACKGROUND: Diabetes is a major risk factor for restenosis and high mortality after percutaneous coronary intervention. The impact of coronary stenting on the clinical outcome of diabetic patients remains controversial. METHOD: The in-hospital and long-term clinical outcomes of 104 consecutive diabetic (60+/-8 year-old, 74 male) and age-matched 193 control (57+/-10 year-old, 162 male) patents underwent coronary stenting between January 1998 and March 1999 at Chonnam National University Hospital were compared. RESULTS: 1) Coronary stenting was successful in 98% of diabetic patients and 97% of non-diabetic patients. Post-procedural minimal luminal diameter (MLD) was not different between two groups(2.89+/-0.42 vs. 2.95+/-0.62 mm), but follow-up MLD was lower in diabetics than that in non-diabetics (1.70+/-0.96 vs. 2.05+/-0.72 mm, P < 0.05). 2) Restenosis rate on follow-up coronary angiograpy was not different between two groups (40.7% in diabetics and 32.0% in non-diabetics. 3) In-hospital outcome was not different between two groups. Long-term clinical follow-up (16+/-11 months) revealed higher overall major adverse cardiac events in diabetics than in non-diabetics (38.7 vs. 30.7 %, P < 0.05). CONCLUSION: Coronary stenting in diabetics can be performed with acceptable short-term results. However, long-term clinical outcome in diabetic patients was worse than in non-diabetics.