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The Patterns and Risk Factors for Subsequent Bladder Recurrence in Patients with Transitional Cell Carcinoma of the Upper Urinary Tract: A Long-Term Follow-Up Study / 대한비뇨기과학회지
Korean Journal of Urology ; : 294-299, 2008.
Artigo em Coreano | WPRIM | ID: wpr-159189
ABSTRACT

PURPOSE:

We wanted to evaluate the patterns and risk factors for subsequent bladder recurrence after surgical management for upper urinary tract transitional cell carcinoma(TCC). MATERIALS AND

METHODS:

Between 1986 and 2004, the medical records of the patients who were diagnosed and surgically treated for upper urinary tract TCC were retrospectively analyzed. A total of 215 patients were enrolled in this study, and the median follow-up duration was 53 months (range 12-240). The bladder recurrence-free survival curve was generated by the Kaplan-Meier method. To investigate the risk factors for subsequent bladder recurrence among the various clinicopathological features, the log rank test and Cox's proportional hazard model were used.

RESULTS:

Recurrence developed in 81 patients(37.7%). Of them, 70 patients (86.4%) had recurred within 24 months, and 76 patients(93.8%) had superficial bladder cancer. Muscle-invasive bladder cancer developed in only 8 patients(9.9%) during follow-up. On univariate analysis, the T stage, age and urine cytology had an influence on bladder recurrence with statistical(borderline) significance. Multivariate analysis revealed that urine cytology was the only independent risk factor for bladder recurrence (p=0.020).

CONCLUSIONS:

Subsequent bladder recurrence after treatment for upper urinary tract transitional cell cancer usually occurred within two years after surgery, and positive urine cytology is an independent prognostic factor for subsequent bladder recurrence.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Recidiva / Sistema Urinário / Bexiga Urinária / Neoplasias da Bexiga Urinária / Carcinoma de Células de Transição / Modelos de Riscos Proporcionais / Prontuários Médicos / Análise Multivariada / Estudos Retrospectivos / Fatores de Risco Tipo de estudo: Estudo de etiologia / Estudo observacional / Estudo prognóstico / Fatores de risco Limite: Humanos Idioma: Coreano Revista: Korean Journal of Urology Ano de publicação: 2008 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Recidiva / Sistema Urinário / Bexiga Urinária / Neoplasias da Bexiga Urinária / Carcinoma de Células de Transição / Modelos de Riscos Proporcionais / Prontuários Médicos / Análise Multivariada / Estudos Retrospectivos / Fatores de Risco Tipo de estudo: Estudo de etiologia / Estudo observacional / Estudo prognóstico / Fatores de risco Limite: Humanos Idioma: Coreano Revista: Korean Journal of Urology Ano de publicação: 2008 Tipo de documento: Artigo