The Effect of Dexpanthenol in Postoperative Patients
Journal of the Korean Society of Coloproctology
;
: 71-74, 2007.
Artigo
em Coreano
| WPRIM
| ID: wpr-160011
ABSTRACT
PURPOSE:
The purpose of this study was to compare the efficacy of dexpanthenol in postoperative patients. Dexpanthenol, the alcohol derivative of pantothenic acid, is believed to be a precursor of acetylcholine through its incorporation into coenzyme-A.METHODS:
From June 2005 to December 2005, 130 curative abdominal surgery, which were divided into a dexpanthenol group with 65 patients and a control group with 65 patients, were prospectively and randomly studied for recovery of bowel motility.RESULTS:
No significant difference was found between the two groups as to incidence of postoperative ileus (16.9% vs. 15.4%, P=0.081), the time to flatus (77.2+/-38.4 vs. 77.9+/-31.9 hours, P=0.90), the time to defecation (5.3+/-2.7 vs. 5.1+/-2.6 days, P=0.77), the time to resumption of meals (7.9+/-4.0 vs. 8.9+/-4.2 days, P=0.17), and the duration of hospital stay (16.4+/-7.8 vs. 17.9+/-11.5 days, P=0.39). CONSLUSIONS Since no differences in the postoperative bowel motility were observed between the two groups, dexpanthenol is not recommended for general surgical use.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Ácido Pantotênico
/
Acetilcolina
/
Incidência
/
Estudos Prospectivos
/
Defecação
/
Íleus
/
Refeições
/
Flatulência
/
Tempo de Internação
Tipo de estudo:
Estudo de incidência
/
Estudo observacional
/
Estudo prognóstico
Limite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Society of Coloproctology
Ano de publicação:
2007
Tipo de documento:
Artigo
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