Association between Cerebral Amyloid Deposition and Clinical Factors Including Cognitive Function in Geriatric Depression: Pilot Study Using Amyloid Positron Emission Tomography
Clinical Psychopharmacology and Neuroscience
;
: 378-382, 2016.
Artigo
em Inglês
| WPRIM
| ID: wpr-160422
ABSTRACT
The purpose of this study was to explore the relationship between cerebral amyloid deposition and overall clinical factors including cognitive functions in geriatric depression by using 18F-florbetaben positron emission tomography. Thirteen subjects aged over 60 years who had a history of major depressive disorder and also had subjective memory complaint were included. Of all subjects, 3 subjects judged as amyloid positive, and the others judged as amyloid negative. Their memory, visuospatial functions and attention abilities were negatively correlated with amyloid deposition in specific brain regions, but their language and recognition abilities were not correlated with any region. The amyloid deposition of the whole brain region was significantly negatively correlated with immediate memory.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Atenção
/
Encéfalo
/
Projetos Piloto
/
Cognição
/
Placa Amiloide
/
Tomografia por Emissão de Pósitrons
/
Depressão
/
Transtorno Depressivo Maior
/
Elétrons
/
Doença de Alzheimer
Idioma:
Inglês
Revista:
Clinical Psychopharmacology and Neuroscience
Ano de publicação:
2016
Tipo de documento:
Artigo
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