A Case of Alternaria alternata Keratitis Isolated from Corneal Tissue / 대한의진균학회지
Korean Journal of Medical Mycology
;
: 27-33, 2015.
Artigo
em Inglês
| WPRIM
| ID: wpr-160770
ABSTRACT
A 71-year-old man presented with pain in the left eye that revealed a 3x3 mm deep corneal stromal infiltrate, with a 2x2 mm epithelial defect. The patient started topical moxifloxacin, voriconazole 2%, and natamycin for 2 weeks. However, the treatment was not effective and the corneal infiltration worsened. Subsequently, the patient underwent therapeutic penetrating keratoplasty. Thick brown/gray mold colonies on Potato Corn Meal Tween 80 agar was isolated from excised corneal tissue and on slide culture many septated, and club-shaped ascospores were revealed. Histological findings also showed numerous hyphae scattered in corneal tissue. A. alternata colonies were confirmed by 18S rRNA sequencing. Intracameral voriconazole was injected every other day for 2 weeks to eliminate remaining fungi on the deep corneal stroma. The remaining corneal infiltration was improved one month after the injection. During 5 months postoperative follow up, the infection did not recurred. In conclusion, deep corneal infection of A. alternata was effectively treated with intracameral voriconazole injection.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Polissorbatos
/
Solanum tuberosum
/
Natamicina
/
Seguimentos
/
Ceratoplastia Penetrante
/
Zea mays
/
Substância Própria
/
Hifas
/
Ágar
/
Alternaria
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Idoso
/
Humanos
Idioma:
Inglês
Revista:
Korean Journal of Medical Mycology
Ano de publicação:
2015
Tipo de documento:
Artigo
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