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Clinical and Epidemiological Study of 1,165 Hospitalized Cases of Rotaviral Gastroenteritis Before and After the Introduction of Rotavirus Vaccine, 2006-2013 / 소아감염
Korean Journal of Pediatric Infectious Diseases ; : 174-180, 2014.
Artigo em Coreano | WPRIM | ID: wpr-161270
ABSTRACT

PURPOSE:

This study was performed to assess the clinical and epidemiological changes after the introduction of the rotavirus vaccine in Korea, as well as to determine the efficacy of the rotavirus vaccine among hospitalized rotaviral gastroenteritis patients over the past two years.

METHODS:

We analyzed yearly and seasonal patterns of 1,165 inpatients who were hospitalized for rotaviral gastroenteritis under the age of 5 years between 2006 and 2013. We also conducted a survey among 460 gastroenteritis patients who were hospitalized between 2012 and 2013 regarding the rotavirus vaccination and the symptoms of gastroenteritis. Among those individuals surveyed, clinical indices were analyzed for 124 patients who were tested positive for the rotavirus antigen.

RESULTS:

The incidence of Rotaviral gastroenteritis have decreased significantly by year 2010. After the introduction and widespread dissemination of the rotavirus vaccine, the onset of the disease and the seasonal peak have been delayed. Overall, the vaccinated group showed a lower rate of positivity than the unvaccinated group. Among the hospitalized rotaviral gastroenteritis patients, the vaccinated group had a shorter hospitalization period, less severe clinical symptoms of gastroenteritis, and better laboratory test results.

CONCLUSIONS:

After introduction of the rotavirus vaccine in Korea, there were two main trends observed 1) the overall level of disease incidence was reduced; 2) the severity of rotaviral gastroenteritis cases also decreased. Based on this data, more children should receive vaccination in order to prevent the rotavirus infection and decrease the severity of rotaviral gastroenteritis.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Infecções por Rotavirus / Estações do Ano / Estudos Epidemiológicos / Epidemiologia / Incidência / Vacinação / Rotavirus / Gastroenterite / Hospitalização / Pacientes Internados Tipo de estudo: Estudo de incidência / Estudo observacional / Estudo prognóstico Limite: Criança / Humanos País/Região como assunto: Ásia Idioma: Coreano Revista: Korean Journal of Pediatric Infectious Diseases Ano de publicação: 2014 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Infecções por Rotavirus / Estações do Ano / Estudos Epidemiológicos / Epidemiologia / Incidência / Vacinação / Rotavirus / Gastroenterite / Hospitalização / Pacientes Internados Tipo de estudo: Estudo de incidência / Estudo observacional / Estudo prognóstico Limite: Criança / Humanos País/Região como assunto: Ásia Idioma: Coreano Revista: Korean Journal of Pediatric Infectious Diseases Ano de publicação: 2014 Tipo de documento: Artigo