A Case of Cancer-Associated Retinopathy with Small Cell Lung Cancer
Journal of the Korean Ophthalmological Society
; : 1171-1176, 2006.
Article
em Ko
| WPRIM
| ID: wpr-161303
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE: To report a case of cancer-associated retinopathy developed in a patient with small cell lung cancer, which is a kind of paraneoplastic syndrome. METHODS: A 78-year-old woman presented complaining of decreased visual acuity and visual field that had developed about 15 days previously. She was diagnosed with small cell lung cancer 1.5 years ago and underwent 3 cycles of chemotherapy. At presentation, the best-corrected visual acuity was hand motion in both eyes and there was no afferent pupillary defect. Slit-lamp biomicroscopic examination revealed no specific abnormality in the anterior segment of either eye, and intraocular pressure was normal. Posterior segment examination demonstrated remarkable arteriolar narrowing in both eyes, but there was little doubt about the presence of an optic nerve lesion such as optic disc edema or pallor. RESULTS: Fluorescein angiography and brain magnetic resonance imaging (MRI) revealed no significant abnormalities. However, electroretinograms (ERG) demonstrated marked reduction in the a and b waves. Visual evoked response was delayed for the latency period. She was treated with systemic steroid, after which her visual acuity gradually improved.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Nervo Óptico
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Palidez
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Síndromes Paraneoplásicas
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Encéfalo
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Imageamento por Ressonância Magnética
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Angiofluoresceinografia
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Acuidade Visual
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Campos Visuais
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Distúrbios Pupilares
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Tratamento Farmacológico
Limite:
Aged
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Female
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Humans
Idioma:
Ko
Revista:
Journal of the Korean Ophthalmological Society
Ano de publicação:
2006
Tipo de documento:
Article