Diabetes-Related Cardiac Dysfunction
Endocrinology and Metabolism
;
: 171-179, 2017.
Artigo
em Inglês
| WPRIM
| ID: wpr-161480
ABSTRACT
The proposal that diabetes plays a role in the development of heart failure is supported by the increased risk associated with this disease, even after correcting for all other known risk factors. However, the precise mechanisms contributing to the condition referred to as diabetic cardiomyopathy have remained elusive, as does defining the disease itself. Decades of study have defined numerous potential factors that each contribute to disease susceptibility, progression, and severity. Many recent detailed reviews have been published on mechanisms involving insulin resistance, dysregulation of microRNAs, and increased reactive oxygen species, as well as causes including both modifiable and non-modifiable risk factors. As such, the focus of the current review is to highlight aspects of each of these topics and to provide specific examples of recent advances in each area.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Estresse Fisiológico
/
Resistência à Insulina
/
Fatores de Risco
/
Espécies Reativas de Oxigênio
/
MicroRNAs
/
Suscetibilidade a Doenças
/
Metabolismo Energético
/
Cardiomiopatias Diabéticas
/
Insuficiência Cardíaca
/
Doenças Metabólicas
Tipo de estudo:
Estudo de etiologia
/
Fatores de risco
Idioma:
Inglês
Revista:
Endocrinology and Metabolism
Ano de publicação:
2017
Tipo de documento:
Artigo
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