A Case Report of Primary Pericardial Malignant Mesothelioma Treated with Pemetrexed and Cisplatin
Journal of Korean Medical Science
;
: 1879-1884, 2017.
Artigo
em Inglês
| WPRIM
| ID: wpr-163184
ABSTRACT
Primary pericardial malignant mesothelioma (PPM) is a very rare malignancy, with an incidence of less than 0.002% and represents less than 5% of all mesotheliomas. The cause of pericardial mesothelioma is uncertain that differ from pleural mesothelioma which is associated with asbestos exposure. This malignancy is terribly aggressive and has very poor prognosis with less than six months of overall survival. We present a case of a 71-year-old woman who was diagnosed with cardiac tamponade caused by PPM and received chemotherapy with pemetrexed and cisplatin for six months. During two years she was alive without disease progression. To better understand the clinical, pathologic features and treatment outcome of this entity, we reviewed 23 cases described in the English literature from 2009, together with our case, provided a total of 24 cases. Based on this review, we suggest that PPM must be considered in patients who have unexplained massive pericardial effusion and recommend chemotherapy with pemetrexed and cisplatin for the better outcome of PPM.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Derrame Pericárdico
/
Prognóstico
/
Amianto
/
Tamponamento Cardíaco
/
Incidência
/
Cisplatino
/
Resultado do Tratamento
/
Progressão da Doença
/
Tratamento Farmacológico
/
Pemetrexede
Tipo de estudo:
Estudo de incidência
/
Estudo prognóstico
Limite:
Idoso
/
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Journal of Korean Medical Science
Ano de publicação:
2017
Tipo de documento:
Artigo
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