Clinical Study on Henoch-Schoenlein Purpura

ABSTRACT

A clinical study on the 41 cases of Henock-Schoenlein purpura in infancy and childhood was made. The results are as followings. 1) The cases were seen mostly in the age group of 4 to 10 yr (63.5%), with the peak incidence in 6~10 yr age group(44%). 2) Males were more affected than females with the Male to Female ratio of 2:1. 3) The peak seasonal incidence was seen in spring with 15 cases (37%) and Winter was in the second place with 12 cases (29%). 4) The previous history of the upper respiratory tract infection was present in 17 cases (41%). 5) The main clinical manifestations were skin rash (100.0%), abdominal pain (73%), nephritis (46%) and joint pain (39%) in order. 6) The most common type of skin rash in Henock-Schoenlein purpura and urticarial wheal with erythematous rash (73%) on the lower extremities. 7) In gastointestinal manifestation of Henock-Schoenlein purpura, abdominal pain was noted in all cases (100%) and next is was vomitting (37%). 8) Joints most often involved were the knee (94%) and ankle (44%) joints and the wrists (31%) and elbow (13%) joints subsequently. 9) The renal manifestation of Henock-Schoenlein purpura was the most serious sign. Proteinuria and micro and gross hematuria were seen in all cases (100%) with renal mvoluement. 10) The Anti-streptolysin O titer was increased in 8 cases (28.5%).