Linear Focal Elastosis Following Striae Distensae: Further Evidence of Keloidal Repair Process in the Pathogenesis of Linear Focal Elastosis
Annals of Dermatology
;
: S141-S143, 2011.
Artigo
em Inglês
| WPRIM
| ID: wpr-16451
ABSTRACT
Linear focal elastosis (LFE) is a rare dermal elastosis characterized by hypertrophic yellowish linear plaques and increased abnormal elastic tissues in the lumbosacral area. Although the pathogenesis of this disorder remains unknown, it may be associated with keloidal repair process (KRP) of elastic tissues in striae distensae (SD), because there have been some reported cases of LFE accompanied by SD. We herein report a 14-year-old boy with LFE following SD in the lumbar region. Our case supports the hypothesis of KRP in the pathogenesis of LFE. Immunohistochemical study for transforming growth factor-beta (TGF-beta) was negative. Therefore, we assume that the pathogenesis of KRP in LFE is different from that of keloid development, which is the TGF-beta signaling pathway.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fator de Crescimento Transformador beta
/
Tecido Elástico
/
Estrias de Distensão
/
Queloide
/
Região Lombossacral
Tipo de estudo:
Estudo de etiologia
Limite:
Adolescente
/
Humanos
Idioma:
Inglês
Revista:
Annals of Dermatology
Ano de publicação:
2011
Tipo de documento:
Artigo
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