A Case of Oseltamivir-Resistant Pandemic Influenza (H1N1 2009) in a Patient with Acute Myeloid Leukemia / 감염과화학요법
Infection and Chemotherapy
;
: 107-111, 2010.
Artigo
em Coreano
| WPRIM
| ID: wpr-164532
ABSTRACT
Oseltamivir is the drug of choice for patients with pandemic influenza (H1N1 2009). However, sporadic cases of oseltamivir resistance have been described worldwide. Up to March 2010, a total of 11 strains (2.2% of tested isolates) of oseltamivir-resistant pandemic influenza (H1N1 2009) have been discovered in South Korea. We report a case of 46-year-old man with acute myeloid leukemia in whom an oseltamivir-resistant pandemic (H1N1) 2009 virus was isolated. Despite high dose oseltamivir therapy for 10 days he had persistent symptoms and showed positive results in repeated real-time RT-PCR for pandemic influenza (H1N1 2009) virus from nasopharyngeal specimen. The patient improved eventually after oseltamivir was replaced by zanamivir inhalation.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Vírus
/
Leucemia Mieloide Aguda
/
Leucemia
/
Inalação
/
Influenza Humana
/
Oseltamivir
/
Zanamivir
/
República da Coreia
/
Pandemias
Limite:
Humanos
País/Região como assunto:
Ásia
Idioma:
Coreano
Revista:
Infection and Chemotherapy
Ano de publicação:
2010
Tipo de documento:
Artigo
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