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Diagnostic accuracy of 64-slice multidetector CT coronary angiography for the evaluation of coronary artery disease / 대한내과학회지
Korean Journal of Medicine ; : 42-53, 2008.
Artigo em Coreano | WPRIM | ID: wpr-164627
ABSTRACT
BACKGROUND/

AIMS:

Invasive coronary angiography remains the gold standard in the diagnosis of coronary artery disease. However, multidetector CT (MDCT) coronary angiography is an emerging technique that is available for the non-invasive detection of coronary artery stenoses. While the diagnostic accuracy of first generation MDCT is limited, recently released 64-slice MDCT has yielded promising results due to increased temporal and spatial resolution. The objective of this study was to investigate the diagnostic accuracy of non-invasive 64-slice MDCT for coronary artery disease.

METHODS:

One hundred one patients (63 males and 38 females; mean age, 63.7+/-10.5 years) undergoing conventional coronary angiography were included in this study. All coronary arteries, including the distal segments and side branches, were analyzed for the presence of significant stenosis (> or =50% diameter stenosis) and compared with of the quantitative coronary angiographic findings.

RESULTS:

Of the 1,440 coronary artery segments studied, 1,348 segments were assessed quantitatively by both MDCT and conventional coronary angiography (94%). Two hundred nine significant stenoses were detected by conventional coronary angiography. On a segment-based analysis, the senisitivity, specificity, and positive and negative predictive values of 64-slice MDCT were 96, 97, 85, and 99%, respectively. On a vessel-based analysis, the sensitivity, specificity, and positive and negative predictive values of 64-slice MDCT were 96, 97, 85, and 99%, respectively. The corresponding values obtained on a patient-based analysis were 100, 94, 97, and 100%, respectively. Coronary calcification was the major cause of false-positive findings.

CONCLUSIONS:

This study demonstrated that 64-slice MDCT coronary angiography is of similar accuracy as conventional coronary angiography for the detection of coronary artery disease. In selected groups of patients, 64-slice MDCT may replace the more invasive coronary angiography.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Doença da Artéria Coronariana / Sensibilidade e Especificidade / Angiografia Coronária / Constrição Patológica / Vasos Coronários / Estenose Coronária Tipo de estudo: Estudo diagnóstico / Estudo prognóstico Limite: Humanos / Masculino Idioma: Coreano Revista: Korean Journal of Medicine Ano de publicação: 2008 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Doença da Artéria Coronariana / Sensibilidade e Especificidade / Angiografia Coronária / Constrição Patológica / Vasos Coronários / Estenose Coronária Tipo de estudo: Estudo diagnóstico / Estudo prognóstico Limite: Humanos / Masculino Idioma: Coreano Revista: Korean Journal of Medicine Ano de publicação: 2008 Tipo de documento: Artigo