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Suspected Case of Iatrogenic Cushing Syndrome Due to Topical Steroid / 대한피부과학회지
Korean Journal of Dermatology ; : 947-950, 2007.
Artigo em Coreano | WPRIM | ID: wpr-16472
ABSTRACT
Chronic exogenous steroid therapy can result in hypothalamic-pituitary-adrenal axis dysfunction; this usually results from systemic steroid therapy, and is rarely associated with topical steroid therapy. We report a case of suspected iatrogenic Cushing syndrome that developed after the treatment of annular pustular psoriasis. The patient applied clobetasol-17-propionate cream (Betabate(R)) 15~30 g daily, for 4 months, without a dermatologist's prescription. After 4 months of application, the following symptoms developed; a moon face; facial flushing; hypertrichosis; central obesity; purple striae; and multiple erythematous scaly annular patches. The development of Cushing syndrome from exogenous corticosteroid treatment was supported by the typical clinical manifestations and the low basal state of the blood cortisol level, which was perhaps due to secondary suppression of the hypothalamic pituitary-adrenal axis. Steroid-containing drugs, especially during childhood, should be used with caution and monitored carefully.
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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Psoríase / Vértebra Cervical Áxis / Hidrocortisona / Síndrome de Cushing / Prescrições / Obesidade Abdominal / Rubor / Hipertricose Limite: Humanos Idioma: Coreano Revista: Korean Journal of Dermatology Ano de publicação: 2007 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Psoríase / Vértebra Cervical Áxis / Hidrocortisona / Síndrome de Cushing / Prescrições / Obesidade Abdominal / Rubor / Hipertricose Limite: Humanos Idioma: Coreano Revista: Korean Journal of Dermatology Ano de publicação: 2007 Tipo de documento: Artigo