Positive family history of glaucoma is a risk factor for increased IOP rather than glaucomatous optic nerve damage (POAG vs OH vs normal control)
Korean Journal of Ophthalmology
;
: 100-104, 1992.
Artigo
em Inglês
| WPRIM
| ID: wpr-16487
ABSTRACT
To elucidate the family history of glaucoma (FHG) as a risk factor for ocular hypertension(OH) vs glaucomatous optic nerve damage, we reviewed the clinical records of 361 primary open-angle glaucoma(POAG) patients, 178 OH subjects, and 927 normal controls randomly selected from an urban medical center eye clinic. The prevalence of a positive FHG was 27% in the POAG patients, 47% in the OH subjects, and 11% in the normal controls. Whereas a positive FHG was a significant risk factor for both OH and glaucoma compared to normal control subjects (OR = 7.56, 95% CI 5.27-10.85, P < .0001 for OH; OR = 3.15, 95% CI 2.31-4.31, P < .0001), it was a risk factor more significantly for OH than for glaucoma being significantly more prevalent in OH than in POAG (OR = 2.40, 95% CI 1.65-3.49, P < .0001). These results suggest the importance of additional risk factors other than IOP for glaucomatous optic nerve damage.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Distribuição Aleatória
/
Doenças do Nervo Óptico
/
Glaucoma de Ângulo Aberto
/
Hipertensão Ocular
/
Saúde da Família
/
Prevalência
/
Inquéritos e Questionários
/
Fatores de Risco
/
Pressão Intraocular
Tipo de estudo:
Ensaio Clínico Controlado
/
Estudo de etiologia
/
Estudo de prevalência
/
Fatores de risco
Limite:
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Korean Journal of Ophthalmology
Ano de publicação:
1992
Tipo de documento:
Artigo
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