Two Cases of Crohn's Disease Presented with Hematochezia in Patients with Hemophilia
Intestinal Research
;
: 35-39, 2011.
Artigo
em Coreano
| WPRIM
| ID: wpr-166474
ABSTRACT
The etiology of Crohn's disease, which is a chronic inflammatory condition that potentially involves any location of the alimentary tract from the mouth to the anus, is unknown. However, there is strong evidence that vascular damage could play a role in the pathogenesis of Crohn's disease. Crohn's disease is mediated by multifocal gastrointestinal infarctions, which occur at an early stage in the disease process. Persistent activation of coagulation in patients with Crohn's disease has been shown. In contrast, hemophilia is an inherited disorder of coagulation. The deficiencies of clotting factors usually involve occult or overt bleeding. The pathogenic mechanisms of Crohn's disease and hemophilia are incompatible. An association between Crohn's disease and hemophilia has not been reported in Korea. We managed 21- and 33-year-old men with Crohn's disease associated with hemophilia, who presented with hematochezia.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Canal Anal
/
Doenças Inflamatórias Intestinais
/
Doença de Crohn
/
Hemofilia A
/
Hemorragia
/
Hemorragia Gastrointestinal
/
Infarto
/
Coreia (Geográfico)
/
Boca
Limite:
Adulto
/
Humanos
/
Masculino
País/Região como assunto:
Ásia
Idioma:
Coreano
Revista:
Intestinal Research
Ano de publicação:
2011
Tipo de documento:
Artigo
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