Experience with Bilateral Risk-Reducing Mastectomy for an Unaffected BRCA Mutation Carrier / 한국유방암학회지
Journal of Breast Cancer
;
: 218-221, 2016.
Artigo
em Inglês
| WPRIM
| ID: wpr-166628
ABSTRACT
Women with BRCA1/2 mutations have a high risk of breast cancer and may opt for risk-reducing mastectomy (RRM). We report a 38-year-old Japanese woman who was diagnosed as a BRCA2 mutation carrier. She underwent prophylactic bilateral skin-sparing mastectomy (SSM) with excision of the nipple and preservation of the areola skin. It is unclear whether a bilateral RRM leads to better survival compared with intensive surveillance. The oncological risk associated with the presence of remnant breast glandular tissue after SSM or nipple-sparing mastectomy has been obscure. We report the first case of RRM for a Japanese BRCA mutation carrier and provide a literature review on risk management for BRCA mutation carriers with a focus on the concepts and procedures of RRM.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Gestão de Riscos
/
Pele
/
Mama
/
Neoplasias da Mama
/
Mastectomia Subcutânea
/
Povo Asiático
/
Procedimentos Cirúrgicos Profiláticos
/
Mastectomia
/
Mamilos
Tipo de estudo:
Estudo de etiologia
Limite:
Adulto
/
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Journal of Breast Cancer
Ano de publicação:
2016
Tipo de documento:
Artigo
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