One-Year Mortality of Acute Kidney Injury in Patients with Acute Myocardial Infarction / 대한신장학회지
Korean Journal of Nephrology
;
: 141-147, 2011.
Artigo
em Inglês
| WPRIM
| ID: wpr-167982
ABSTRACT
PURPOSE:
Acute kidney injury (AKI) is a common complication during hospitalization and is an accepted risk factor for in-hospital mortality. However, the association of severity of AKI with the long-term risk of death is not well known. This study aimed to investigate the incidence and clinical significance of AKI in patients with acute myocardial infarction (AMI).METHODS:
To examine the effect of the severity of AKI on 1-year risk of death following AMI, we performed an observational study of 1,224 patients admitted for AMI. We evaluated the association between AKI and all-cause mortality. Patients with maintaining hemodialysis treatment (n=7), and who died during hospitalization (n=71) were excluded. Remaining 1146 patients were divided into three groups according to the Acute Kidney Injury Network (AKIN) criteria (Stage-1, -2, and-3). The primary end point of the study was 1-year all-cause mortality after hospital discharge. The relation between the severity of AKI and 1-year mortality after AMI was analyzed.RESULTS:
AKI was developed in 222/1,146 (19.3%) patients during the hospital stay. Adjusted hazard ratio for 1-year mortality was 3.064 (95% CI 1.618 to 5.803, p=0.001), 6.112 (95% CI 2.344 to 15.935, p<0.001) and 20.030 (95% CI 5.428 to 73.912, p<0.001) in stage-1, -2, and stage-3 AKI groups compared with that of no AKI group.CONCLUSION:
The severity of AKI is strongly related to 1-year all cause mortality in patients with AMI.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Incidência
/
Fatores de Risco
/
Diálise Renal
/
Mortalidade Hospitalar
/
Evolução Fatal
/
Injúria Renal Aguda
/
Hospitalização
/
Tempo de Internação
/
Infarto do Miocárdio
Tipo de estudo:
Estudo de etiologia
/
Estudo de incidência
/
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Humanos
Idioma:
Inglês
Revista:
Korean Journal of Nephrology
Ano de publicação:
2011
Tipo de documento:
Artigo
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