Vitamin C-iontophoresis in Melasma / 대한피부과학회지
Korean Journal of Dermatology
;
: 285-291, 2001.
Artigo
em Coreano
| WPRIM
| ID: wpr-168963
ABSTRACT
BACKGROUND:
An inhibitory effect of ascorbic acid(AsA) on melanogenesis has been described. Iontophoresis is emerging technologies capable of enhancing drug penetration through stratum corneum, the principal barrier to percutaneous absorption.OBJECTIVE:
Our purpose of this study was to evaluate the efficacy of vitamin C-iontophoresis in patients of melasma.METHODS:
The treatment was performed twice weekly in 15 volunteer patients for a period of 6 weeks by application of vitamin C under a constant direct current of 0.4-0.8A for 15minutes. Clinical evaluations using the Melasma Area and Severity Index(MASI) and bioengineering measurement using Chromameter CR 300(R) were taken before and after treatment.RESULTS:
Decreased MASI and light reflectance were noted at the end of 6 weeks, significant clinical improvement in the melasma was seen compared to before treatment.CONCLUSION:
Vitamin C-iontophoresis is an effective, noninvasive treatment of melasma without significant side-effects.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Ácido Ascórbico
/
Absorção Cutânea
/
Vitaminas
/
Voluntários
/
Iontoforese
/
Bioengenharia
/
Melanose
Limite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Dermatology
Ano de publicação:
2001
Tipo de documento:
Artigo
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