Vogt-Koyanagi-Harada disease occurring during pegylated interferon-alpha2b and ribavirin combination therapy for chronic hepatitis C / 대한간학회지
The Korean Journal of Hepatology
;
: 61-65, 2011.
Artigo
em Inglês
| WPRIM
| ID: wpr-169273
ABSTRACT
Vogt-Koyanagi-Harada (VKH) disease is a multisystem syndrome characterized by ocular (uveitis and retinal detachment), neurological (headache, tinnitus, and meningitis), and integumentary (vitiligo, alopecia, and poliosis) involvement. Although the pathogenesis of VKH disease is not well understood, an autoimmune T-cell response to a melanocyte-associated antigen is considered to be a cause of VKH disease. The complex immunological response to interferon and ribavirin may induce or exacerbate the autoimmune condition; however, VKH disease is a very rare complication associated with interferon therapy in chronic hepatitis C. We report a case of VKH disease occurring during pegylated interferon-alpha2b and ribavirin combination therapy for chronic hepatitis C.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Antivirais
/
Polietilenoglicóis
/
Ribavirina
/
Prednisolona
/
Imageamento por Ressonância Magnética
/
Angiofluoresceinografia
/
Tomografia Computadorizada por Raios X
/
Síndrome Uveomeningoencefálica
/
Interferon-alfa
/
Hepatite C Crônica
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
The Korean Journal of Hepatology
Ano de publicação:
2011
Tipo de documento:
Artigo
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