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The effect of single incision laparoscopic cholecystectomy on systemic oxidative stress: a prospective clinical trial
Annals of Surgical Treatment and Research ; : 179-183, 2017.
Artigo em Inglês | WPRIM | ID: wpr-170002
ABSTRACT

PURPOSE:

Single incision laparoscopic cholecystectomy (SILC) has become a more frequently performed method for benign gallbladder diseases all over the world. The effects of SILC technique on oxidative stress have not been well documented. The aim of this study was to evaluate the effect of laparoscopic cholecystectomy techniques on systemic oxidative stress by using ischemia modified albumin (IMA).

METHODS:

In total, 70 patients who had been diagnosed with benign gallbladder pathology were enrolled for this prospective study. Twenty-one patients underwent SILC and 49 patients underwent laparoscopic cholecystectomy (LC). All operations were performed under a standard anesthesia protocol. Serum IMA levels were analysed before operation, 45 minutes and 24 hours after operation.

RESULTS:

Demographics and preoperative characteristics of the patients were similiar in each group. The mean duration of operation was 37.5 ± 12.5 and 44.6 ± 14.3 minutes in LC and SILC group, respectively. In both groups, there was no statistically significant difference in hospital stay, operative time, or conversion to open surgery. Operative technique did not effect the 45th minute and 24th hour IMA levels. However, prolonged operative time (>30 minutes) caused an early increase in the level of IMA. Twenty-fourth hour IMA levels were not different.

CONCLUSION:

SILC is an effective and safe surgical prosedure for benign gallbladder diseases. Independent of the surgical technique for cholecystectomy, the prolonged operative time could increase the tissue ischemia.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Patologia / Colecistectomia / Cálculos Biliares / Demografia / Estudos Prospectivos / Colecistectomia Laparoscópica / Laparoscopia / Estresse Oxidativo / Duração da Cirurgia / Conversão para Cirurgia Aberta Tipo de estudo: Guia de Prática Clínica / Estudo observacional Limite: Humanos Idioma: Inglês Revista: Annals of Surgical Treatment and Research Ano de publicação: 2017 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Patologia / Colecistectomia / Cálculos Biliares / Demografia / Estudos Prospectivos / Colecistectomia Laparoscópica / Laparoscopia / Estresse Oxidativo / Duração da Cirurgia / Conversão para Cirurgia Aberta Tipo de estudo: Guia de Prática Clínica / Estudo observacional Limite: Humanos Idioma: Inglês Revista: Annals of Surgical Treatment and Research Ano de publicação: 2017 Tipo de documento: Artigo