A Case of Acute Infectious Purpura Fulminans / 대한피부과학회지

ABSTRACT

Purpura fulminans(PF) is a devastating disorder characterized by rapidly progressing hemorrhagic necrosis of the skin, circulatory collapse, and disseminated intravascular coagulation. Histopathologically skin lesions show thrombi within the dermal vessels, a sparse perivascular mononuclear infiltrate, and epidermal necrosis. PF can be classified into three distinct categories: acute infectious PF (sepsis associated PF), hemostasis induced PF, and idiopathic PF. We describe a case of acute infectious PF occurring in 65-year old female with pneumococcal sepsis.