A Case of Hydroxychloroquine Induced Acute Generalized Exanthematous Pustulosis Confirmed by Accidental Oral Provocation
Annals of Dermatology
;
: 102-105, 2010.
Artigo
em Inglês
| WPRIM
| ID: wpr-172922
ABSTRACT
Acute generalized exanthematous pustulosis (AGEP) is a clinical reaction pattern that is principally drug induced and this is characterized by acute, nonfollicular sterile pustules on a background of edematous erythema. Hydroxychloroquine (HCQ) has been widely used to treat rheumatic and dermatologic diseases and HCQ has been reported to be an uncommon cause of AGEP. A 38-year-old woman with a 1-year history of dermatomyositis and polyarthralgia was treated with HCQ due to a lack of response to a previous medication. Three weeks after starting HCQ therapy, the pustular skin lesion developed and then this resolved after the HCQ was withdrawn and steroid treatment was started. A similar pustular eruption developed after HCQ was accidentally readministered.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pele
/
Artralgia
/
Dermatomiosite
/
Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos
/
Eritema
/
Pustulose Exantematosa Aguda Generalizada
/
Hidroxicloroquina
Limite:
Adulto
/
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Annals of Dermatology
Ano de publicação:
2010
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS