Stool DNA Testing for Colorectal Cancer: Development and Advances
Intestinal Research
;
: 134-141, 2012.
Artigo
em Inglês
| WPRIM
| ID: wpr-17299
ABSTRACT
Screening for colorectal cancer is one of the most effective public health interventions. Although colonoscopy is the preferred method in many settings, colonoscopy can miss lesions, interval neoplasms can arise after a normal colonoscopy, and some patients refuse to undergo colonoscopy. In the last decade, detection of neoplasia-associated genetic alterations in the stool has become feasible. First-generation stool DNA tests demonstrated better sensitivity for colorectal cancer than fecal occult blood tests. Improvements to stool DNA tests have made them more sensitive and less complex. The newer marker panels can detect colorectal cancer and even the majority of advanced adenomas, regardless of location in the colon. This review summarizes the development and advances to stool DNA testing for colorectal cancer.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
DNA
/
Neoplasias Colorretais
/
Adenoma
/
Programas de Rastreamento
/
Saúde Pública
/
Colonoscopia
/
Colo
/
Sangue Oculto
Tipo de estudo:
Estudo prognóstico
/
Estudo de rastreamento
Limite:
Humanos
Idioma:
Inglês
Revista:
Intestinal Research
Ano de publicação:
2012
Tipo de documento:
Artigo
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