Cut-off value of D-dimer for prediction of deep venous thrombosis before treatment in ovarian cancer / 부인종양
Journal of Gynecologic Oncology
;
: 98-102, 2012.
Artigo
em Inglês
| WPRIM
| ID: wpr-17309
ABSTRACT
OBJECTIVE:
The purpose of the present study was to elucidate the incidence of deep venous thrombosis (DVT) before treatment in ovarian cancer and the appropriate cut-off value of D-dimer (DD) for the diagnosis of DVT.METHODS:
Between July 2007 and October 2008, eighty seven patients with presumed ovarian cancer (final diagnosis ovarian cancer, n=59; borderline malignancy, n=28) were enrolled. Measurement of DD levels and subsequent venous ultrasonography were performed before treatment.RESULTS:
The mean DD level was 4.1 microg/mL. Subsequent venous ultrasonography revealed DVT in 14 of 87 (16.1%) patients (ovarian cancer, 12 cases; borderline malignancy, 2 cases). None were found to have developed DVT if they had a DD level of <1.5 microg/mL. If 1.5 microg/mL was used as a cut-off value for DD levels to diagnose DVT, sensitivity, specificity, positive predictive value, and negative predictive value were 100%, 61.6%, 33.3%, and 100%. There was noclinical onset of postoperative pulmonary thromboembolism.CONCLUSION:
Our data suggest that presumed ovarian cancer patients with at least more than 1.5 microg/mL should be examined using venous ultrasonogaphy to detect DVT.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Neoplasias Ovarianas
/
Produtos de Degradação da Fibrina e do Fibrinogênio
/
Incidência
/
Sensibilidade e Especificidade
/
Trombose Venosa
Tipo de estudo:
Estudo diagnóstico
/
Estudo de incidência
/
Estudo prognóstico
Limite:
Humanos
Idioma:
Inglês
Revista:
Journal of Gynecologic Oncology
Ano de publicação:
2012
Tipo de documento:
Artigo
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