Successful Treatment of Newly Developed, Intractable Digital Ulcers and Gangrene with Bosentan in Systemic Sclerosis
Journal of Rheumatic Diseases
;
: 193-197, 2016.
Artigo
em Inglês
| WPRIM
| ID: wpr-173095
ABSTRACT
In systemic sclerosis, digital ulcers and gangrene are somewhat common clinical characteristics of obliterative vasculopathy. These manifestations increase morbidities, such as pain, infections, and acroosteolysis. However, patient responses to the appropriate treatments are often inadequate. We treated a patient with systemic sclerosis who had a refractory digital ulcer and gangrene with bosentan, an endothelin receptor antagonist, and observed improvement. Here we systematically review this case.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Escleroderma Sistêmico
/
Úlcera
/
Receptores de Endotelina
/
Acro-Osteólise
/
Gangrena
Limite:
Humanos
Idioma:
Inglês
Revista:
Journal of Rheumatic Diseases
Ano de publicação:
2016
Tipo de documento:
Artigo
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