A Case of Sarcoidosis That Improved upon Discontinuation of Etanercept
Journal of Rheumatic Diseases
;
: 187-192, 2016.
Artigo
em Inglês
| WPRIM
| ID: wpr-173096
ABSTRACT
A 31-year-old man who had been prescribed etanercept over a 3-year period for treatment of ankylosing spondylitis presented with newly developed dry cough, chills, myalgia, and weight loss. Chest computed tomography showed multiple reticulonodular pulmonary infiltrates and bilateral mediastinal, hilar, and peribronchial lymphadenopathy. Biopsy of a paratracheal lymph node revealed chronic granulomatous inflammation without necrosis, and the serum angiotensin-converting enzyme level was elevated. Sarcoidosis was diagnosed. His laboratory and radiological findings, and clinical symptoms improved only after discontinuation of etanercept without treatment. Although etanercept-induced sarcoidosis is rare, this case report suggests that sarcoidosis should be considered in the differential diagnosis of patients treated with the tumor necrosis factor inhibitor.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Sarcoidose
/
Espondilite Anquilosante
/
Tórax
/
Biópsia
/
Redução de Peso
/
Fator de Necrose Tumoral alfa
/
Tosse
/
Calafrios
/
Diagnóstico Diferencial
/
Mialgia
Tipo de estudo:
Estudo diagnóstico
Limite:
Adulto
/
Humanos
Idioma:
Inglês
Revista:
Journal of Rheumatic Diseases
Ano de publicação:
2016
Tipo de documento:
Artigo
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