Hemodynamic Effects of Nicardipine Measured by Esophageal Doppler Monitor during Gynecologic Laparoscopic Surgery
Anesthesia and Pain Medicine
;
: 17-21, 2008.
Artigo
em Inglês
| WPRIM
| ID: wpr-173150
ABSTRACT
BACKGROUND:
The authors performed this study to investigate the hemodynamic effect of nicardipine using an esophageal Doppler monitor (EDM) during gynecologic laparoscopic surgery.METHODS:
Forty patients scheduled to undergo gynecologic laparoscopic surgery, were divided into two groups; the control group (Group C) and the nicardipine group (Group N). Pneumoperitoneum was initiated using CO2 gas and the intraperitoneal pressure was kept under 12 mmHg. Hemodynamic parameters at critical points were measured using EDM, i.e., before skin incision (T1), 5, 10 and 15 min after the initiation of pneumoperitoneum (T2, T3 and T4), and 5 min after deflation (T5).RESULTS:
Mean arterial pressure (MAP) was significantly lower in Group N patients than in Group C patients at 5 and 10 min after the initiation of pneumoperitoneum (T2 and T3) (P < 0.05). No significant heart rate (HR) differences were observed between the two study groups. Cardiac output (CO), peak velocity (PV) and corrected flow time (FTC) were significantly higher in Group N at 10 min after the initiation of pneumoperitoneum (T3) (all P < 0.05).CONCLUSIONS:
The nicardipine continuous infusion at 0.5?2.0microg/ kg/min is effective at attenuating hemodynamic changes after pneumoperitoneum during gynecologic laparoscopic surgery.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Compostos Organotiofosforados
/
Pneumoperitônio
/
Pele
/
Débito Cardíaco
/
Nicardipino
/
Laparoscopia
/
Pressão Arterial
/
Frequência Cardíaca
/
Hemodinâmica
Limite:
Humanos
Idioma:
Inglês
Revista:
Anesthesia and Pain Medicine
Ano de publicação:
2008
Tipo de documento:
Artigo
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