Two Cases of Systemic Lupus Erythematosus with Cerebrovascular Involvement / 영남의대학술지
Yeungnam University Journal of Medicine
;
: 371-380, 1998.
Artigo
em Coreano
| WPRIM
| ID: wpr-173325
ABSTRACT
Systemic lupus erythematosus(SLE) is an autoimmune disease which may affect many different organs and disclose various clinical manifestations. Recently central nervous system(CNS) involvement has been recognized as an increasingly significant contributor to morbidity and mortality of SLE. The clinical manifestations of CNS-lupus are highly variable and range from mild cognitive dysfunction, movement disorder, headache, psychosis to life-threatening stroke and coma. Among the neuropsychiatric disorders encountered in patients with SLE, cerebrovascular disease has been a relatively rare complication. The diagnosis and management of CNS-lupus is difficult because of the lack of useful diagnostic methods. If, cerebrovascular involvement is suspected, then aggressive treatment such as high dose steroid, immunosuppressive therapy, plasma exchange, may be required to reduce high mortality rate. We experienced 2 cases cerebrovascular disease occurring in SLE patients which presented with various neuropsychiatric manifestations. They were diagnosed as CNS-lupus by neuropsychiatric symptoms, brain MRI, and EEG, and showed good response to high dose steroid pulse therapy.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Troca Plasmática
/
Transtornos Psicóticos
/
Doenças Autoimunes
/
Encéfalo
/
Imageamento por Ressonância Magnética
/
Mortalidade
/
Coma
/
Acidente Vascular Cerebral
/
Diagnóstico
/
Eletroencefalografia
Tipo de estudo:
Estudo diagnóstico
/
Estudo prognóstico
Limite:
Humanos
Idioma:
Coreano
Revista:
Yeungnam University Journal of Medicine
Ano de publicação:
1998
Tipo de documento:
Artigo
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