A case of subcutaneous plasmacytomas of vessel puncture site in multiple myeloma after autologous stem cell transplantation / 대한내과학회지

ABSTRACT

We report a case of a 61-year-old man with Durie-Salmon stage IB, kappa light chain type, multiple myeloma (MM), who relapsed 6 months after autologous hematopoietic stem cell transplantation (HSCT). One month after vinblastin-mitoxantrone-dexamethasone chemotherapy, he presented with multiple subcutaneous plasmacytomas. These lesions were confined to previous vessel puncture sites such as subclavian central catheter insertion site, anchoring site and sampling site. He had no past history of plasmacytoma. After additional treatment of etoposide, cisplatin, solumedrol, cytosine arabinoside, the plasmacytomas decreased or disappeared. But blasts reappeared in his peripheral blood and the size of the plasmacytomas increased. This case represents the rare report of refractory MM presenting as multiple subcutaneous plasmacytomas with specific tropism to the sites of previous trauma.