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Bacterial etiology in hospitalized patients with acute exacerbations of chronic obstructive pulmonary disease / 대한내과학회지
Korean Journal of Medicine ; : 309-314, 2009.
Article em Ko | WPRIM | ID: wpr-174771
Biblioteca responsável: WPRO
ABSTRACT
(AECOPD). While critically ill patients requiring admission need proper antibiotic treatment for the causative pathogen, little is known about the bacterial etiology of AECOPD in Korea. We therefore studied the bacterial etiology of hospitalized patients with COPD in our institution. METHODS: The study enrolled 149 patients who were admitted to the hospital in Sungnam with the diagnosis of AECOPD between July 1, 2004 and June 1, 2007. We retrospectively reviewed the clinical data and results of sputum cultures. RESULTS: Of the 149 subjects with sputum collected, 51% (76 cases) had positive bacterial cultures [age 70.7+/- 9.2 years (mean+/- SD); 116 males] of sputum. Pseudomonas aeruginosa (24 cases, 30.4%) was the organism cultured in sputum most commonly, followed by Streptococcus pneumonia (15 cases, 18.9%), Acinetobacter sp. (9 cases, 11.4%), and Klebsiella pneumonia (7 cases, 8.9%). Patients whose FEV1 was 50% (17/96 vs. 4/53, respectively, p=0.002). Patients taking systemic steroids also had a higher rate of sputum culture of P. aeruginosa (85.7%). CONCLUSIONS: P. aeruginosa was the pathogen most commonly isolated in hospitalized patients with COPD. This species should be considered when physicians select empirical antibiotics to treat patients with AECOPD.
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Texto completo: 1 Índice: WPRIM Assunto principal: Pneumonia / Pseudomonas aeruginosa / Escarro / Esteroides / Streptococcus / Infecções Bacterianas / Acinetobacter / Estudos Retrospectivos / Estado Terminal / Doença Pulmonar Obstrutiva Crônica Tipo de estudo: Etiology_studies / Observational_studies Limite: Humans País/Região como assunto: Asia Idioma: Ko Revista: Korean Journal of Medicine Ano de publicação: 2009 Tipo de documento: Article
Texto completo: 1 Índice: WPRIM Assunto principal: Pneumonia / Pseudomonas aeruginosa / Escarro / Esteroides / Streptococcus / Infecções Bacterianas / Acinetobacter / Estudos Retrospectivos / Estado Terminal / Doença Pulmonar Obstrutiva Crônica Tipo de estudo: Etiology_studies / Observational_studies Limite: Humans País/Região como assunto: Asia Idioma: Ko Revista: Korean Journal of Medicine Ano de publicação: 2009 Tipo de documento: Article