Intravenous albumin for the prevention of contrast-induced nephropathy in patients with liver cirrhosis and chronic kidney disease undergoing contrast-enhanced CT
Kidney Research and Clinical Practice
;
: 106-111, 2012.
Artigo
em Inglês
| WPRIM
| ID: wpr-174799
ABSTRACT
BACKGROUND:
The purpose of this study was to evaluate the incidence of contrast-induced nephropathy (CIN), and the effect of intravenous albumin for prophylaxis of CIN in patients with liver cirrhosis (LC) and chronic kidney disease (CKD).METHODS:
We conducted a retrospective study of 81 subjects with LC and CKD (estimated glomerular filtration rate (eGFR) or =25% or > or =0.5mg/dL in serum creatinine level.RESULTS:
Overall, CIN developed in three patients (3.7%). Of the 81 subjects, 43 received sodium bicarbonate solution and 38 received albumin. Both groups were comparable with regard to age, sex, diabetes mellitus, and baseline eGFR. The albumin group showed a significantly poorer liver function profile. CIN incidence did not differ significantly between the groups it occurred in one (2.3%) of the 43 subjects receiving sodium bicarbonate and two (5.3%) of the 38 subjects receiving albumin (P=0.6). However, the albumin group showed a significantly smaller increase in body weight (P=0.03).CONCLUSION:
The incidence of CIN in patients with LC and CKD undergoing contrast-enhanced CT after preventive measures was relatively low. The incidence of CIN was not significantly different between sodium bicarbonate and albumin groups.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Peso Corporal
/
Incidência
/
Estudos Retrospectivos
/
Bicarbonato de Sódio
/
Creatinina
/
Diabetes Mellitus
/
Insuficiência Renal Crônica
/
Taxa de Filtração Glomerular
/
Fígado
/
Cirrose Hepática
Tipo de estudo:
Estudo de incidência
/
Estudo observacional
/
Estudo prognóstico
Limite:
Humanos
Idioma:
Inglês
Revista:
Kidney Research and Clinical Practice
Ano de publicação:
2012
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS