Carney Complex: Eleven Open Heart Operations in a Single Family
The Korean Journal of Thoracic and Cardiovascular Surgery
;
: 471-473, 2017.
Artigo
em Inglês
| WPRIM
| ID: wpr-175180
ABSTRACT
Herein, we report on a family with Carney complex. Four members of the family underwent a total of 11 open heart operations as well as 9 other operations to treat extrathoracic masses. All the family members met at least 2 major clinical criteria and 1 supplemental criterion. We analyzed their genomic loci, including the protein kinase A regulatory subunit 1 gene. The results revealed no specific mutations, except for a common single nucleotide polymorphism. This case series of Carney complex emphasizes the importance of close longitudinal follow-up because of the high rate of tumor recurrence irrespective of the site. Clinicians should not overlook the specific features of familial myxoma.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Recidiva
/
Seguimentos
/
Proteínas Quinases Dependentes de AMP Cíclico
/
Polimorfismo de Nucleotídeo Único
/
Complexo de Carney
/
Coração
/
Mixoma
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Humanos
Idioma:
Inglês
Revista:
The Korean Journal of Thoracic and Cardiovascular Surgery
Ano de publicação:
2017
Tipo de documento:
Artigo
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