A Case of Autoimmune Hepatitis Following Acute Hepatitis A / 대한소화기학회지
The Korean Journal of Gastroenterology
;
: 315-318, 2011.
Artigo
em Coreano
| WPRIM
| ID: wpr-175648
ABSTRACT
The pathogenesis of autoimmune hepatitis (AIH) is unclear, but viral infections have been proposed as a potential trigger in patients with genetic predisposition. We report a case of AIH following acute hepatitis A (AHA). A 57-year-old woman presented with fatigue and pitting edema for last 3 months. She had been diagnosed as an AHA 15 months ago based on clinical features, biochemical tests and positive HAV IgM antibody at a local clinic. Her biochemical tests was normalized one month after AHA diagnosis, but the serum levels of aminotransferase started to rise four months after AHA diagnosis. Antinuclear antibody was positive at a titer of 140, and anti-smooth muscle antibody was also positive. Hypergammaglobulinemia and liver pathology were typical for AIH. The patients had a score of 17 according to the International Autoimmune Hepatitis Group's system. She was given prednisolone and azathioprine and showed complete response to immunosuppressive therapy. The present case is the first report on AIH triggered by AHA in Korea.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Aspartato Aminotransferases
/
Autoanticorpos
/
Azatioprina
/
Prednisolona
/
Anticorpos Antinucleares
/
Doença Aguda
/
Hepatite Autoimune
/
Alanina Transaminase
/
Hepatite A
/
Hipergamaglobulinemia
Limite:
Feminino
/
Humanos
Idioma:
Coreano
Revista:
The Korean Journal of Gastroenterology
Ano de publicação:
2011
Tipo de documento:
Artigo
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